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Pyrazinamide (PZA) testing is suspended due to issues with the manufacturer’s kit. ARUP will continue testing the other first-line drugs: rifampin, isoniazid, and ethambutol. If PZA susceptibility testing is required during this test delay, contact your local public health laboratory or the CDC for pncA gene testing for PZA resistance mutations.
Expected turnaround time for a result, beginning when ARUP has received the specimen.
21-28 days
Reference Interval
Normal range/expected value(s) for a specific disease state. May also include abnormal ranges.
By report
Interpretive Data
May include disease information, patient result explanation, recommendations, or details of testing.
The interpretation provided is based on results for the following drugs at the stated concentrations: Drugs tested: Ethambutol: 5.0 µg/mL, isoniazid: 0.1 µg/mL (0.4 µg/mL if resistant to 0.1 µg/mL), pyrazinamide: 100 µg/mL, and rifampin: 1.0 µg/mL.
This procedure screens isolates of M. tuberculosis complex for drug resistance. The procedure does not use serial dilutions to provide quantitative MIC values. Single critical concentrations for each antimycobacterial agent used have been defined by the United States Public Health Service.
Compliance Category
FDA
Note
Additional information related to the test.
M. tuberculosis complex isolates mono-resistant to Pyrazinamide (PZA) will be further identified to species by PCR. Additional charges apply.
Hotline History
N/A
CPT Codes
The American Medical Association Current Procedural Terminology (CPT) codes published in ARUP's Laboratory Test Directory are provided for informational purposes only. The codes reflect our interpretation of CPT coding requirements based upon AMA guidelines published annually. CPT codes are provided only as guidance to assist clients with billing. ARUP strongly recommends that clients confirm CPT codes with their Medicare administrative contractor, as requirements may differ. CPT coding is the sole responsibility of the billing party. ARUP Laboratories assumes no responsibility for billing errors due to reliance on the CPT codes published.
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
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